Opening a treasure chest: glomerular proteome analyses of formalin-fixed paraffin-embedded kidney tissue in the investigation of diabetic nephropathy.
نویسنده
چکیده
Worldwide, diabetic nephropathy (DN) persists as a major complication of diabetes mellitus (DM), affecting approximately one-third of DM patients [1]. DN is characterized by development of progressive glomerulosclerotic and tubulointerstitial kidney lesions gradually leading to an increasing loss of functioning kidney parenchyma [2]. As therapeutic intervention is frequently insufficient to prevent development of DN and its progression to end-stage renal 1695
منابع مشابه
Proteome analysis of laser microdissected glomeruli from formalin-fixed paraffin-embedded kidneys of autopsies of diabetic patients: nephronectin is associated with the development of diabetic glomerulosclerosis.
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ورودعنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 27 5 شماره
صفحات -
تاریخ انتشار 2012